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Propagating Differential Gene Expression in Protein Interaction Networks

Werner Van Belle*, Nancy Gerits, Ugo Moens; Propagating Differential Gene Expression in Protein Interaction Networks; Bioinformatics; YellowCouch Scientific; February 2008

The Transcriptional Regulation & Cell-specific Expression of the MAPK-Activated Protein Kinase MK5

Nancy Gerits, Alexey Shiryaev, Sergiy Kostenko, Helle Klenow, Olga Shiryaeva, Mona Johannessen and Ugo Moens; Cellular & Molecular Biology Letters; 22 September 2008

Oncogenic potentials of the human polyomavirus regulatory proteins

Moens U, Van Ghelue M, Johannessen M. (2007). Cellular and Molecular Life Sciences, 64(13):1656-1678

Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein

Johannessen M, Delghandi MP, Rykx A, Dragset M, Vandenheede JR, Van Lint J, Moens U. (2007). Journal of Biological Chemistry, 282(20):14777-14787

Multisite phosphorylation of the cAMP response element-binding protein (CREB) by a diversity of protein kinases

Johannessen M, Moens U. - Frontiers in Bioscience, 12:1814-1832 (2007).

Human Polyomaviruses: Molecular Mechanisms for Transformation and their Association with Cancers

Moens U., Van Ghelue M., Johannessen M. (2007). New Research on Oncogenic Viruses by Tunely E.I. (ed.), pp. 1-63, Nova Science Publisher, New York ISBN: 1-60021-585-8 - Invited review

Confidence Intervals on Micro Array Measurment of Differntially Expressed Genes; A Case Study on the effect of MK5, TAF4 and FKRP on the transriptome.

Werner Van Belle*, Nancy Gerits, Kirsti Jakobsen, Vigdis Brox, Marijke Van Ghelue, Ugo Moens; Gene Regulation and Systems Biology (lapress); May 2007

Modulation of F-actin rearrangement by the cyclic AMP/PKA pathway is mediated by MAPKAP Kinase 5 and requires PKA-induced nuclear export of MK5

Nancy Gerits, Theresa Mikalsen, Sergiy Kostenko, Alexey Shiryaev, Mona Johannessen and Ugo Moens* - Journal of Biological Chemistry 282(51):37232-37243

Transgenic mice expressing constitutive active MAPKAPK5 display gender-dependent differences in exploration and activity

Nancy Gerits, Werner Van Belle, Ugo Moens - Behavioral and Brain Functions; Biomed Central; volume 3; nr 58; November 2007

Gamma-Glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells

Pandur, S.,Pankiv, S., Johannessen, M., Moens, U., and Huseby, N.E. Free Radical Research, 41(12):1376-84 (2007)

Protein Kinase Inhibitors

Nancy Gerits and Ugo Moens - Encyclopedia of Molecular Pharmacology - In press - ISBN 978-3-540-38916-3 (2007) - Invited review

Toll like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediated the effect of CpG-oligonucleotides.

Martin-Armas, M., Simon-Santamaria, J., Pettersen, I., Moens, U., Smedsrød, B., Sveinbjørnsson, B - J. Hepatol., in press.

The functional diversity of the four-and-a-half-LIM only protein FHL2 and its possible implications in diseases.

Johannessen, M., Møller, S., Hansen, T., Moens, U., Van Ghelue, M. - Cell Mol Life Sci. 2006. Jan 2; [Epub ahead of print].

Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway.

Pankiv, P., Møller, S., Bjørkøy, G., Moens, U., Huseby, NE. - Biochim Biophys Acta. 2006 Feb;1760(2):151-7. Epub 2005 Dec 9

Inhibitors of signal transduction protein kinases as targets for cancer therapy

Theresa Mikalsen, Nancy Gerits, and Ugo Moens*

In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice

Nancy Gerits*, Sergiy Kostenko and Ugo Moens - 10th August 2006

Immunity and autoimmunity induced by polyomaviruses. Clinical, experimental and theoretical aspects.

Rekvig OP, Bendiksen S, and Moens U. Chapter In Human polyomaviruses and disease - Adv Exp Med Biol. 2006;577:117-47

Transcription of genes in response to activated cAMP/protein kinase A signaling pathway: There is more to it than CREB.

Johannessen, M. and Moens, U. Chapter in: Trends in cellular Signaling. Caplin, D.E. (ed.). Nova Publisher. ISBN:1-59454-633-9.

The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH3T3 cells.

Pedersen Delghandi, M., Johannessen, M., and Moens, U. (2005) - Cellular Signal.17: 1343-1351.

Sequence- and position-dependent tagging protects extracellular-regulated kinase 3 protein from 26S proteasome-mediated degradation.

Mikalsen , T., Johannessen, M., and Moens, U. (2005) - Int. J. Biochem. Cell Biol. 37:2513-2520.