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Studies on the function of the mitogen-activated protein kinase MK5/PRAK
This project aims at defining the biological role of the mitogen-activated protein kinase activated protein kinase MAPKAPK-5 (MK5 or PRAK).
Studies on the polymorphism in the genome of polyomavirus BK: implications for cell tropism and the pathology
This project wants to isolate and characterise naturally occurring BKV variants. Knowledge on the naturally circulating BKV strains in patients may help us to define the possible implications of genome diversity with respect to cell tropism and pathogenicity, and may enable us to design successful therapeutic strategies.
Characterization of BKV agnoprotein and analysis of its function and regulation
Identifications of the function(s) and regulation of the viral protein, agnoprotein.